Postdoc in the Altindis Lab - Biology Department, Boston College

Project Name: Inhibiting IGF-1 receptor signaling via viral insulins to stop IGF-1 mediated growth and cancer progression

Altindis Lab at Boston College Biology Department is seeking a highly motivated postdoctoral fellow for a translational research project studying the role of viral insulins on insulin/IGF-1 signaling system, growth and cancer progression. We recently made a surprising discovery and showed that viruses encode insulin/IGF-1 like sequences, viral insulin/IGF-1 like peptides (VILPs)1-5. While most of the VILPs are natural agonists of the human receptors, we showed that two VILPs are natural antagonists of the IGF-1 receptor6,7. We seek a productive and independent postdoctoral researcher to join us working on further characterization of the viral insulins. The main goal of this project to further characterize viral insulins and determine their effects of their inhibitory action on growth and cancer progression. The position is available from September 2022.

Please see the full posting here.